Pediatric Pharmacology and Drug therapy

Pediatrics Pharmacology

#Pharmacology is the scientific study of drugs and their effects, especially in the treatment of Disease. For a drug to be effective, it must be present in the body at an appropriate  Concentration, meaning it must be properly absorbed, distributed, metabolized, and then  eliminated—a process called pharmacokinetics. Similarly, an effective drug must be able to
 reach its appropriate target and produce the desired effect by relying on biochemical and physiological interactions between the drug and the body—a process called pharmacodynamics.

Developmental aspects of drug disposition and response have largely been excluded from pharmacology research. The changing nature of immature organisms adds a unique complexity to #pediatric and #obstetric pharmacology research and requires a systems-biology approach to fully understand the inter-relationships of the variables involved. The lack of knowledge in the field has been borne out by medication disasters, such as administration of chloramphenicol to newborns who lacked mature metabolic pathways and developed #cardiovascular collapse, or who were exposed in utero to teratogens, such as retinoic acid and angiotensin-converting enzyme inhibitors and suffered the resultant anomalies.

Drug Therapy 

Drug therapy has been one of the most significant and positive influences on paediatric health in recent decades. The chance of a child’s dying before the age five has fallen from an estimated 25% to 30% – with the vast majority of deaths being caused by infectious diseases – to approximately 0.6% in most developed countries

#Drugtreatment in children differs from that in adults, most obviously because it is usually based on weight or surface area. Doses (and dosing intervals) differ because of age-related variations in drug absorption, distribution, metabolism, and #elimination. A child cannot safely receive an adult drug dose, nor can it be assumed that a child’s dose is proportional to an adult’s dose.

Adverse Effects and Toxicity

Children are generally subject to the same #adverseeffects as adults, but they have increased risk with certain drugs because of differences in #pharmacokinetics or because of drug effects on growth and development.

Younger children are at especially high risk of accidental poisoning when they discover and take caregivers’ vitamins or drugs. Infants are also at risk of toxicity from drugs used by adults; toxicity can occur prenatally when they are exposed via placental transfer or postnatally when exposed through breast milk.

We are glad to announce 3rd World Congress on Pediatric Neurology and Pediatric Surgery on October 01-02, 2018 at Osaka, Japan. We hope it is the rigt platform for you to explore your research talk internationally and have the networking with the eminent speakers all over the world.

We are accepting abstracts through the following link:https://pediatricneurology.neurologyconference.com/abstract-submission.php

For any queries you can feel free to contact our team @ neuropediatric2018conference@gmail.com

Contact no: +17025085200 Ext: 8045

Happy to Assist You.....